Endocannabinoids and the regulation of body fat: the smoke is clearing.

نویسنده

  • Tamas L Horvath
چکیده

Endocannabinoids, endogenous ligands of cannabinoid receptor type 1 (CB1), have emerged as novel and important regulators of energy homeostasis. A report in this issue demonstrates reduced body weight, fat mass, and appetite in CB1-/- mice. Examination of the underlying mechanisms reveals a dual role for endocannabinoids as they affect both appetite and peripheral lipolysis.

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عنوان ژورنال:
  • The Journal of clinical investigation

دوره 112 3  شماره 

صفحات  -

تاریخ انتشار 2003